5NCW
Structure of the trypsin induced serpin-type proteinase inhibitor, miropin (V367K/K368A mutant).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serpin-type proteinase inhibitor, miropin | polymer | 334 | 37488.9 | 1 | UniProt (G8UQY8) Pfam (PF00079) | Tannerella forsythia | |
| 2 | B (B) | Serpin-type proteinase inhibitor, miropin | polymer | 41 | 4481.1 | 1 | UniProt (G8UQY8) | Tannerella forsythia | |
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | F, G, H, I (A) | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
| 6 | J, K, L, M, N... (A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 7 | P (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 8 | Q, R (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | S, T (A, B) | water | water | 18.0 | 448 | Chemie (HOH) |
Sequence modifications
A: 0 - 328 (UniProt: G8UQY8)
B: 368 - 408 (UniProt: G8UQY8)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gln 135 | Arg 198 | conflict |
| Lys 328 | Val 391 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 368 | Lys 392 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41970.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1196.6 | |
| All* | Total formula weight | 43166.6 |
