5NB7
Complement factor D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement factor D | polymer | 230 | 24597.0 | 1 | UniProt (P00746) Pfam (PF00089) | Homo sapiens (Human) | Adipsin,C3 convertase activator,Properdin factor D |
| 2 | B, C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | D (A) | 1-[2-[(1~{R},3~{S},5~{R})-3-[(6-bromanylpyridin-2-yl)carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxidanylidene-ethyl]indazole-3-carboxamide | non-polymer | 483.3 | 1 | Chemie (8NQ) | |||
| 4 | E (A) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 16 - 243 (UniProt: P00746)
| PDB | External Database | Details |
|---|---|---|
| Ser 244 | - | expression tag |
| Ala 245 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24597.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 639.6 | |
| All* | Total formula weight | 25236.5 |
