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5N8M

Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex A)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RISC-loading complex subunit TARBP2polymer21523012.31UniProt (Q15633)
Pfam (PF00035)
Homo sapiens (Human)TAR RNA-binding protein 2,Trans-activation-responsive RNA-binding protein
2B
(B)
RNA (5'-R(*UP*UP*AP*AP*UP*UP*AP*UP*CP*UP*AP*UP*UP*CP*CP*GP*UP*AP*CP*UP*U)-3')polymer216534.81synthetic construct
3C
(C)
RNA (5'-R(*GP*UP*AP*CP*GP*GP*AP*AP*UP*AP*GP*AP*UP*AP*AP*UP*UP*AP*AP*UP*U)-3')polymer216747.11synthetic construct
Sequence modifications
A: 16 - 227 (UniProt: Q15633)
PDBExternal DatabaseDetails
Gly 13-expression tag
Gly 14-expression tag
Ser 15-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight36294.2
All*Total formula weight36294.2
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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