5N8C
Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 304 | 33546.1 | 2 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | C, D, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, I (A, B) | (2~{S})-3-azanyl-2-[[(1~{R})-5-[2-[4-[[2-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]ethynyl]-2,3-dihydro-1~{H}-inden-1-yl]amino]-3-methyl-~{N}-oxidanyl-butanamide | non-polymer | 473.6 | 2 | Chemie (8Q8) | |||
| 4 | F, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 303 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67092.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1279.7 | |
| All* | Total formula weight | 68371.8 |
