5N84
TTK kinase domain in complex with Mps-BAY2b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein kinase TTK | polymer | 313 | 36131.3 | 1 | UniProt (P33981) Pfam (PF00069) | Homo sapiens (Human) | Phosphotyrosine picked threonine-protein kinase,PYT |
| 2 | B (A) | ~{N}-cyclopropyl-4-[8-(2-methylpropylamino)imidazo[1,2-a]pyrazin-3-yl]benzamide | non-polymer | 349.4 | 1 | Chemie (8Q5) | |||
| 3 | C, D, E, F, G (A) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 4 | H (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 5 | I (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 519 - 808 (UniProt: P33981)
| PDB | External Database | Details |
|---|---|---|
| Met 496 | - | initiating methionine |
| His 497 | - | expression tag |
| His 498 | - | expression tag |
| His 499 | - | expression tag |
| His 500 | - | expression tag |
| His 501 | - | expression tag |
| His 502 | - | expression tag |
| Ser 503 | - | expression tag |
| Ser 504 | - | expression tag |
| Gly 505 | - | expression tag |
| Val 506 | - | expression tag |
| Asp 507 | - | expression tag |
| Leu 508 | - | expression tag |
| Gly 509 | - | expression tag |
| Thr 510 | - | expression tag |
| Glu 511 | - | expression tag |
| Asn 512 | - | expression tag |
| Leu 513 | - | expression tag |
| Tyr 514 | - | expression tag |
| Phe 515 | - | expression tag |
| Gln 516 | - | expression tag |
| Ser 517 | - | expression tag |
| Met 518 | - | expression tag |
| Leu 797 | Pro 797 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36131.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 584.5 | |
| All* | Total formula weight | 36715.8 |
