5N7P
cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 3-amino-5-(pyrrolidin-1-yl)-1H-pyrazole-4-carbonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41113.8 | 1 | UniProt (P25321) Pfam (PF00069) | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
| 2 | B (B) | cAMP dependent protein kinase inhibitor alpha-like protein | polymer | 19 | 1993.3 | 1 | UniProt (by SIFTS) (G3HK48) | Cricetulus griseus | |
| 3 | C (A) | 5-azanyl-3-pyrrolidin-1-yl-1~{H}-pyrazole-4-carbonitrile | non-polymer | 177.2 | 1 | Chemie (E9Q) | |||
| 4 | D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43107.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 295.4 | |
| All* | Total formula weight | 43402.5 |
