5N7B
Understanding the singular conformational landscape of the Tn antigens: Sulfur-for- oxygen substitution in the glycosidic linkage provides new insights into molecular recognition by an antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Ig heavy chain V-III region J606,Ig lambda-1 chain V region S43 | polymer | 244 | 25758.3 | 1 | UniProt (P01801) UniProt (P01727) Pfam (PF07686) | Mus musculus (Mouse) | |
| 2 | B (I) | APD(CG6)RP(NH2) peptide | polymer | 7 | 670.8 | 1 | synthetic construct | ||
| 3 | C, D, E, F, G... (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | J (I) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) | |||
| 5 | K, L (H, I) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
H: 1 - 118 (UniProt: P01801)
H: 1007 - 1117 (UniProt: P01727)
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | Glu 1 | conflict |
| Gln 3 | Lys 3 | conflict |
| Gln 5 | Glu 5 | conflict |
| Gly 100 | - | insertion |
| Val 101 | - | insertion |
| Gly 102 | Thr 100 | conflict |
| Gln 103 | Gly 101 | conflict |
| Thr 114 | Leu 110 | conflict |
| Ser 990 | - | linker |
| Ser 991 | - | linker |
| Ser 992 | - | linker |
| Gly 993 | - | linker |
| Gly 994 | - | linker |
| Gly 995 | - | linker |
| Gly 996 | - | linker |
| Ser 997 | - | linker |
| Gly 998 | - | linker |
| Gly 999 | - | linker |
| Gly 1000 | - | linker |
| Gly 1001 | - | linker |
| Gly 1002 | - | linker |
| Ser 1003 | - | linker |
| Ser 1004 | - | linker |
| Gly 1005 | - | linker |
| Ser 1006 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Asp 1008 | Gln 20 | conflict |
| Ile 1009 | Ala 21 | conflict |
| Ala 1087 | Thr 99 | conflict |
| Ile 1094 | Met 106 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26429.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 655.7 | |
| All* | Total formula weight | 27084.8 |
