5N5I

Crystal Structure of VIM-1 metallo-beta-lactamase in complex with hydrolysed meropenem

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Beta-lactamase VIM-1	polymer	253	26898.8	1	UniProt (Q9XAY4) Pfam (PF00753)	Pseudomonas aeruginosa	Class B carbapenemase VIM-1,Metallo-beta-lactamase,Metallo-beta-lactamase VIM-1,Metallobeta-lactamase,VIM-1,VIM-1 metallo-beta lactamase,VIM-1 metallo-beta-lactamase,VIM-1 protein
2	B, C, D (A)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
3	E (A)	(2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid	non-polymer		401.5	1	Chemie (LMP)
4	F (A)	water	water		18.0	85	Chemie (HOH)

Sequence modifications

A: 21 - 266 (UniProt: Q9XAY4)

PDB	External Database	Details
Lys 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26898.8
Non-Polymers*	Number of molecules	4
	Total formula weight	597.7
All*	Total formula weight	27496.5

*Water molecules are not included.