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5N3A

cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 4-methyl-5-(1-methylimidazol-2-yl)-1,3-thiazol-2-amine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP-dependent protein kinase catalytic subunit alphapolymer35341193.71UniProt (P25321)Cricetulus griseus (Chinese hamster)PKA C-alpha
2B
(B)
cAMP dependent protein kinase inhibitor alpha-like proteinpolymer191993.31UniProt (by SIFTS) (G3HK48)Cricetulus griseus
3C, D
(A)
DIMETHYL SULFOXIDEnon-polymer78.12Chemie (DMS)
4E
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
5F
(A)
4-methyl-5-(1-methyl-1H-imidazol-2-yl)-1,3-thiazol-2-aminenon-polymer194.31Chemie (46P)
6G, H
(A, B)
waterwater18.0247Chemie (HOH)
Sequence modifications
A: 0 - 350 (UniProt: P25321)
PDBExternal DatabaseDetails
Gly -2-expression tag
His -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43187.1
Non-Polymers*Number of molecules4
Total formula weight468.7
All*Total formula weight43655.8
*Water molecules are not included.

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PDB entries from 2026-02-25

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