5N2F
Structure of PD-L1/small-molecule inhibitor complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Programmed cell death 1 ligand 1 | polymer | 126 | 14402.5 | 1 | UniProt (Q9NZQ7) Pfam (PF07686) In PDB | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
2 | B | Programmed cell death 1 ligand 1 | polymer | 124 | 14126.2 | 1 | UniProt (Q9NZQ7) Pfam (PF07686) In PDB | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
3 | B | 4-[[4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-2,5-bis(fluoranyl)phenyl]methylamino]-3-oxidanylidene-butanoic acid | non-polymer | 497.5 | 1 | Chemie (8HW) | |||
4 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 18 - 134 (UniProt: Q9NZQ7)
B: 18 - 134 (UniProt: Q9NZQ7)
PDB | External Database | Details |
---|---|---|
Ala 135 | - | expression tag |
Ala 136 | - | expression tag |
Ala 137 | - | expression tag |
Leu 138 | - | expression tag |
Glu 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 135 | - | expression tag |
Ala 136 | - | expression tag |
Ala 137 | - | expression tag |
Leu 138 | - | expression tag |
Glu 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28528.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 497.5 | |
All* | Total formula weight | 29026.1 |