5N2D
Structure of PD-L1/small-molecule inhibitor complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Programmed cell death 1 ligand 1 | polymer | 144 | 16734.3 | 4 | UniProt (Q9NZQ7) Pfam (PF07686) In PDB | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
2 | B, D | ~{N}-[2-[[2,6-dimethoxy-4-[(2-methyl-3-phenyl-phenyl)methoxy]phenyl]methylamino]ethyl]ethanamide | non-polymer | 448.6 | 2 | Chemie (8J8) | |||
3 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 134 (UniProt: Q9NZQ7)
PDB | External Database | Details |
---|---|---|
Ala 135 | - | expression tag |
Ala 136 | - | expression tag |
Ala 137 | - | expression tag |
Leu 138 | - | expression tag |
Glu 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
His 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 66937.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 897.1 | |
All* | Total formula weight | 67834.1 |