5MZ8

Crystal structure of aldehyde dehydrogenase 21 (ALDH21) from Physcomitrella patens in complex with the reaction product succinate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	aldehyde dehydrogenase 21	polymer	515	56637.8	4	UniProt (A9SS48) Pfam (PF00171)	Physcomitrella patens subsp. patens (Moss)
2	E, JA, R, YA (A, C, B, D)	SUCCINIC ACID	non-polymer		118.1	4	Chemie (SIN)
3	AA, BA, BB, CA, CB... (B, D, A, C)	1,2-ETHANEDIOL	non-polymer		62.1	41	Chemie (EDO)
4	HA, HB, O, P, Q... (B, D, A, C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	7	Chemie (PEG)
5	AB, KA, S, ZA (D, C, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	IB, JB, KB, LB (A, B, C, D)	water	water		18.0	648	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 497 (UniProt: A9SS48)

PDB	External Database	Details
Met -17	-	initiating methionine
Gly -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Ser -7	-	expression tag
Gln -6	-	expression tag
Asp -5	-	expression tag
Pro -4	-	expression tag
Asn -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	226551.2
Non-Polymers*	Number of molecules	56
	Total formula weight	4128.4
All*	Total formula weight	230679.6

*Water molecules are not included.