5MZ4

Crystal Structure of full-lengh CSFV NS3/4A

Replaces:  5LKL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Genome polyprotein,Genome polyprotein	polymer	752	83669.3	2	UniProt (P19712) Pfam (PF05578) Pfam (PF07652) Pfam (PF00271) Pfam (PF20907) In PDB	Classical swine fever virus (strain Alfort) (CSFV)
2		water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B: 1 - 37 (UniProt: P19712)

PDB	External Database	Details
Met -19	-	initiating methionine
Ala -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

A, B: 42 - 732 (UniProt: P19712)

PDB	External Database	Details
Gly 38	-	linker
Ser 39	-	linker
Gly 40	-	linker
Ser 41	-	linker
Ala 204	Ser 1752	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	167338.7
All*	Total formula weight	167338.7

*Water molecules are not included.