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5MY9

Crystal structure of human 14-3-3 sigma in complex with LRRK2 peptide pS935

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
Leucine-rich repeat serine/threonine-protein kinase 2polymer131565.61UniProt (Q5S007)Homo sapiensDardarin
3C, D, E
(A)
CALCIUM IONnon-polymer40.13Chemie (CA)
4F
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5G, H
(A, P)
waterwater18.0383Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28108.5
Non-Polymers*Number of molecules4
Total formula weight155.7
All*Total formula weight28264.2
*Water molecules are not included.

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PDB entries from 2024-12-18

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