5MV9

Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Unconventional myosin-VIIa	polymer	527	61069.3	1	UniProt (Q13402) Pfam (PF00784) Pfam (PF21989) Pfam (PF00373) Pfam (PF02174)	Homo sapiens (Human)
2	B (B)	cDNA FLJ51329, highly similar to Harmonin	polymer	130	14247.1	1	UniProt (B4DV53) Pfam (PF00595) UniProt (by SIFTS) (Q9Y6N9)	Homo sapiens (Human)
3	C, D (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	E, F (A, B)	water	water		18.0	328	Chemie (HOH)

Sequence modifications

A: 1702 - 2215 (UniProt: Q13402)

PDB	External Database	Details
Met 1689	-	initiating methionine
Gly 1690	-	expression tag
Ser 1691	-	expression tag
Ser 1692	-	expression tag
His 1693	-	expression tag
His 1694	-	expression tag
His 1695	-	expression tag
His 1696	-	expression tag
His 1697	-	expression tag
His 1698	-	expression tag
Ser 1699	-	expression tag
Ser 1700	-	expression tag
Gly 1701	-	expression tag

B: 428 - 552 (UniProt: B4DV53)

PDB	External Database	Details
Gly 423	-	expression tag
Ala 424	-	expression tag
Met 425	-	expression tag
Gly 426	-	expression tag
Ser 427	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75316.3
Non-Polymers*	Number of molecules	2
	Total formula weight	118.1
All*	Total formula weight	75434.4

*Water molecules are not included.