5MTY

Dibenzosuberone inhibitor 8e in complex with p38 MAPK

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitogen-activated protein kinase 14	polymer	360	41343.2	1	UniProt (Q16539) Pfam (PF00069) In PDB	Homo sapiens (Human)	MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
2	A	~{N}-[2,4-bis(fluoranyl)-5-[[14-(2-hydroxyethylcarbamoyl)-2-oxidanylidene-6-tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]amino]phenyl]thiophene-2-carboxamide	non-polymer		547.6	1	Chemie (HB9)
3	A	octyl beta-D-glucopyranoside	non-polymer		292.4	2	Chemie (BOG)
4		water	water		18.0	36	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41343.2
Non-Polymers*	Number of molecules	3
	Total formula weight	1132.3
All*	Total formula weight	42475.5

*Water molecules are not included.