5MPO

Crystal structure of human molybdopterin synthase complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Molybdopterin synthase sulfur carrier subunit	polymer	106	11838.4	2	UniProt (O96033) Pfam (PF02597)	Homo sapiens (Human)	MOCO1-A,Molybdenum cofactor synthesis protein 2 small subunit,Molybdenum cofactor synthesis protein 2A,MOCS2A,Molybdopterin-synthase small subunit,Sulfur carrier protein MOCS2A
2	C, D (C, D)	Molybdopterin synthase catalytic subunit	polymer	154	17252.8	2	UniProt (O96007) Pfam (PF02391)	Homo sapiens (Human)	MOCO1-B,Molybdenum cofactor synthesis protein 2 large subunit,Molybdenum cofactor synthesis protein 2B,MOCS2B,Molybdopterin-synthase large subunit,MPT synthase large subunit
3	E, F, G (A, C, D)	water	water		18.0	7	Chemie (HOH)

Sequence modifications

A, B: 7 - 88 (UniProt: O96033)

PDB	External Database	Details
Met -17	-	initiating methionine
Gly -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Val -6	-	expression tag
Asp -5	-	expression tag
Leu -4	-	expression tag
Gly -3	-	expression tag
Thr -2	-	expression tag
Glu -1	-	expression tag
Asn 0	-	expression tag
Leu 1	-	expression tag
Tyr 2	-	expression tag
Phe 3	-	expression tag
Gln 4	-	expression tag
Ser 5	-	expression tag
Met 6	-	expression tag

C, D: 27 - 179 (UniProt: O96007)

PDB	External Database	Details
Met 26	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	58182.3
All*	Total formula weight	58182.3

*Water molecules are not included.