5MOI

Crystal structure of human IgE-Fc epsilon 3-4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Ig epsilon chain C region	polymer	223	24920.1	6	UniProt (P01854) Pfam (PF07654)	Homo sapiens (Human)
2	G (G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		707.6	1	In PDB GlyTouCan (G00027MO)
3	H, I, K (H, I, K)	alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G94626GC)
4	J (J)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G55220VL)
5	L (L)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose	branched		504.4	1	In PDB GlyTouCan (G72618IM)
6	M, N, O, P, Q... (A, B, D)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	6	Chemie (PEG)
7	R, T, U, W, X... (B, C, D, E, F)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
8	S (C)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
9	AA, BA, CA, DA, EA... (B, C, D, E, F...)	water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 328 - 547 (UniProt: P01854)

PDB	External Database	Details
Ala 325	-	expression tag
Asp 326	-	expression tag
Pro 327	-	expression tag
Gln 371	Asn 252	conflict
Gln 383	Asn 264	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	149520.9
Branched	Number of molecules	6
	Total formula weight	5179.6
Non-Polymers*	Number of molecules	13
	Total formula weight	1268.6
All*	Total formula weight	155969.1

*Water molecules are not included.