5MM9
VIM-2_2b. Metallo-beta-Lactamase Inhibitors by Bioisosteric Replacement: Preparation, Activity and Binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metallo-beta-lactamase VIM-17 | polymer | 241 | 25596.4 | 2 | UniProt (B5KVR9) Pfam (PF00753) | Pseudomonas aeruginosa | Verona integron-encoded metallo-beta-lactamase |
| 2 | C, D, E, G, H... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, K (A, B) | (2~{R})-2-diethoxyphosphoryl-5-phenyl-pentane-1-thiol | non-polymer | 316.4 | 2 | Chemie (8SH) | |||
| 4 | I (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 553 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 300 (UniProt: B5KVR9)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51192.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1049.6 | |
| All* | Total formula weight | 52242.3 |
