5ML5
Human p38alpha MAPK in complex with imidazolyl pyridine inhibitor 11b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 360 | 41343.2 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (Human) | MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a |
| 2 | B, C, D (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 3 | Chemie (BOG) | |||
| 3 | E (A) | 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-methylsulfanyl-1~{H}-imidazol-5-yl]pyridin-2-yl]propanamide | non-polymer | 492.6 | 1 | Chemie (1VI) | |||
| 4 | F (A) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41343.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1369.7 | |
| All* | Total formula weight | 42712.9 |
