5ML0
Bromodomain of Mouse PCAF with (R)-4-chloro-2-methyl-5-((1-methylpiperidin-3-yl)amino)pyridazin-3(2H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone acetyltransferase KAT2B | polymer | 110 | 13191.2 | 1 | UniProt (Q9JHD1) Pfam (PF00439) | Mus musculus (Mouse) | Histone acetyltransferase PCAF,Histone acetylase PCAF,Lysine acetyltransferase 2B,P300/CBP-associated factor,P/CAF |
| 2 | B (A) | 4-chlorol-2-methyl-5-[[(3~{R})-1-methylpiperidin-3-yl]amino]pyridazin-3-one | non-polymer | 256.7 | 1 | Chemie (P2L) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A: 723 - 831 (UniProt: Q9JHD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 722 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13191.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 380.9 | |
| All* | Total formula weight | 13572.1 |
