5MHH
Crystal structure of engineered human lipocalin 2 carrying p-boronophenylalanine at position 36
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neutrophil gelatinase-associated lipocalin | polymer | 188 | 21870.5 | 1 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (Human) | NGAL,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Lipocalin-2,Oncogene 24p3,Siderocalin LCN2,p25 |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 1 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| His 28 | Gln 48 | engineered mutation |
| Phe 52 | Tyr 72 | engineered mutation |
| Ser 87 | Cys 107 | engineered mutation |
| Trp 125 | Lys 145 | engineered mutation |
| Asn 134 | Lys 154 | engineered mutation |
| Ser 179 | - | expression tag |
| Ala 180 | - | expression tag |
| Trp 181 | - | expression tag |
| Ser 182 | - | expression tag |
| His 183 | - | expression tag |
| Pro 184 | - | expression tag |
| Gln 185 | - | expression tag |
| Phe 186 | - | expression tag |
| Glu 187 | - | expression tag |
| Lys 188 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21870.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 22158.7 |
