5MGW
Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phenylalanine--tRNA ligase, mitochondrial | polymer | 406 | 47488.9 | 1 | UniProt (O95363) Pfam (PF01409) Pfam (PF03147) | Homo sapiens (Human) | Phenylalanyl-tRNA synthetase,PheRS |
| 2 | B (A) | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) | |||
| 3 | C (A) | water | water | 18.0 | 522 | Chemie (HOH) |
Sequence modifications
A: 10 - 415 (UniProt: O95363)
| PDB | External Database | Details |
|---|---|---|
| Cys 383 | Arg 419 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47488.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 165.2 | |
| All* | Total formula weight | 47654.1 |
