5MGH
Crystal structure of pathogenic mutants of human mitochodnrial PheRS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phenylalanine--tRNA ligase, mitochondrial | polymer | 405 | 47445.8 | 1 | UniProt (O95363) Pfam (PF01409) Pfam (PF03147) In PDB | Homo sapiens (Human) | Phenylalanyl-tRNA synthetase,PheRS |
2 | A | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) | |||
3 | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A: 11 - 415 (UniProt: O95363)
PDB | External Database | Details |
---|---|---|
Ala 49 | Pro 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 47445.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 165.2 | |
All* | Total formula weight | 47611.0 |