5MG2
Crystal structure of the second bromodomain of human TAF1 in complex with BAY-299 chemical probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription initiation factor TFIID subunit 1 | polymer | 137 | 15882.8 | 1 | UniProt (P21675) Pfam (PF00439) | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | B, C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | 6-(3-oxidanylpropyl)-2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione | non-polymer | 429.5 | 1 | Chemie (7M8) | |||
| 4 | F (A) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 1501 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1499 | - | expression tag |
| Met 1500 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15882.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 615.7 | |
| All* | Total formula weight | 16498.5 |
