5MES
MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 162 | 18227.6 | 1 | UniProt (P97287) UniProt (Q07820) Pfam (PF00452) In PDB | Mus musculus (Mouse) | Bcl-2-related protein EAT/mcl1,Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | H | Heavy Chain | polymer | 230 | 24488.5 | 1 | Homo sapiens | ||
| 3 | L | Light Chain | polymer | 226 | 24157.5 | 1 | Homo sapiens | ||
| 4 | A | (5~{R},13~{S},17~{S})-5-[[4-chloranyl-3-(2-phenylethyl)phenyl]methyl]-13-[(4-chlorophenyl)methyl]-8-methyl-1,4,8,12,16-pentazatricyclo[15.8.1.0^{20,25}]hexacosa-20(25),21,23-triene-3,7,15,26-tetrone | non-polymer | 782.8 | 1 | Chemie (7LT) | |||
| 5 | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A: 172 - 240 (UniProt: P97287)
A: 241 - 327 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 166 | - | expression tag |
| Pro 167 | - | expression tag |
| Leu 168 | - | expression tag |
| Gly 169 | - | expression tag |
| Ser 170 | - | expression tag |
| Glu 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66873.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 782.8 | |
| All* | Total formula weight | 67656.3 |
