5MC3
Crystal Structure of Glu412Lys mutant of Human Prolidase with Mn ions and GlyPro ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Xaa-Pro dipeptidase | polymer | 484 | 53799.2 | 2 | UniProt (P12955) Pfam (PF05195) Pfam (PF00557) | Homo sapiens (Human) | X-Pro dipeptidase,Imidodipeptidase,Peptidase D,Proline dipeptidase,Prolidase |
| 2 | C, L (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, M (A, B) | HYDROXIDE ION | non-polymer | 17.0 | 2 | Chemie (OH) | |||
| 4 | E, N (A, B) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | Homo sapiens | ||
| 5 | F, O (A, B) | PROLINE | non-polymer | 115.1 | 2 | Chemie (PRO) | Homo sapiens | ||
| 6 | G, P (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H, I, J, K, Q... (A, B) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 8 | W, X (A, B) | water | water | 18.0 | 939 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 489 (UniProt: P12955)
| PDB | External Database | Details |
|---|---|---|
| Lys 412 | Glu 412 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 107598.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1491.2 | |
| All* | Total formula weight | 109089.5 |
