5MBZ
Crystal Structure of Ser202Phe mutant of Human Prolidase with Mn ions and GlyPro ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Xaa-Pro dipeptidase | polymer | 484 | 53859.2 | 2 | UniProt (P12955) Pfam (PF05195) Pfam (PF00557) | Homo sapiens (Human) | X-Pro dipeptidase,Imidodipeptidase,Peptidase D,Proline dipeptidase,Prolidase |
| 2 | C, D, L, M (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | E, N (A, B) | HYDROXIDE ION | non-polymer | 17.0 | 2 | Chemie (OH) | |||
| 4 | F, O (A, B) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | Homo sapiens | ||
| 5 | G, P (A, B) | PROLINE | non-polymer | 115.1 | 2 | Chemie (PRO) | Homo sapiens | ||
| 6 | H, I, Q, R (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | J, K (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 8 | S (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | T, U (A, B) | water | water | 18.0 | 1126 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 489 (UniProt: P12955)
| PDB | External Database | Details |
|---|---|---|
| Phe 202 | Ser 202 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 107718.4 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1084.0 | |
| All* | Total formula weight | 108802.4 |
