5M8M
Crystal structure of human tyrosinase related protein 1 in complex with kojic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 5,6-dihydroxyindole-2-carboxylic acid oxidase | polymer | 446 | 50619.3 | 4 | UniProt (P17643) Pfam (PF00264) | Homo sapiens (Human) | DHICA oxidase,Catalase B,Glycoprotein 75,Melanoma antigen gp75,Tyrosinase-related protein 1,TRP1 |
| 2 | E, J, O, T (E, J, O, T) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 4 | In PDB GlyTouCan (G21290RB) | |||
| 3 | F, K, U (F, K, U) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 3 | In PDB GlyTouCan (G86851RC) | |||
| 4 | G, H, I, L, N... (G, H, I, L, N...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 5 | M (M) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 6 | P (P) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G26032DN) | |||
| 7 | R (R) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G21381MC) | |||
| 8 | BA, CA, DA, FA, GA... (B, C, D, A) | ZINC ION | non-polymer | 65.4 | 9 | Chemie (ZN) | |||
| 9 | AA, EA, HA, LA (A, B, C, D) | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | non-polymer | 142.1 | 4 | Chemie (KOJ) | |||
| 10 | IA (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 11 | MA, NA, OA, PA (A, B, C, D) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 202477.0 | |
| Branched | Number of molecules | 20 |
| Total formula weight | 10182.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1378.3 | |
| All* | Total formula weight | 214037.9 |
