5M84

Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpA mRNA 5' cap analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Eukaryotic translation initiation factor 4E	polymer	190	22145.1	2	UniProt (P63073) Pfam (PF01652)	Mus musculus (house mouse)	mRNA cap-binding protein,eIF-4F 25 kDa subunit
2	C, F (A, B)	[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl hydrogen phosphate	non-polymer		817.5	2	Chemie (YDZ)
3	D, E (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	G, H (A, B)	water	water		18.0	133	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44290.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1819.3
All*	Total formula weight	46109.5

*Water molecules are not included.