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5M7Z

Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSepG mRNA 5' cap analog (beta-Se-ARCA D2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Eukaryotic translation initiation factor 4Epolymer19022145.14UniProt (P63073)
Pfam (PF01652)
Mus musculus (Mouse)mRNA cap-binding protein,eIF-4F 25 kDa subunit
2E, G
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
3F, I, J
(A, B, C)
[[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-selanyl-phosphoryl] [(2~{R},3~{S},4~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphatenon-polymer880.43Chemie (7LO)
4H
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5K, L, M, N
(A, B, C, D)
waterwater18.0434Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight88580.5
Non-Polymers*Number of molecules6
Total formula weight2860.9
All*Total formula weight91441.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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