5M7U

Structure of human O-GlcNAc hydrolase with new iminocyclitol type inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein O-GlcNAcase	polymer	916	103020.9	2	UniProt (O60502) Pfam (PF07555) In PDB	Homo sapiens (Human)	OGA,Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Meningioma-expressed antigen 5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase,NCOAT
2	A, B	2-[(2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-[3-[3-(trifluoromethyl)phenyl]propyl]pyrrolidin-2-yl]-~{N}-methyl-ethanamide	non-polymer		390.4	2	Chemie (XHA)
3		water	water		18.0	47	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	206041.8
Non-Polymers*	Number of molecules	2
	Total formula weight	780.8
All*	Total formula weight	206822.6

*Water molecules are not included.