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5M7B

Blood group synthase AAGlyB in complex with UDP and cryoprotected with glycerol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHisto-blood group ABO system transferasepolymer29834654.01UniProt (P16442)
Pfam (PF03414)
In PDB
Homo sapiens (Human)Fucosylglycoprotein 3-alpha-galactosyltransferase,Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-galactosyltransferase,Histo-blood group A transferase,A transferase,Histo-blood group B transferase,B transferase,NAGAT
2AMANGANESE (II) IONnon-polymer54.91Chemie (MN)
3AURIDINE-5'-DIPHOSPHATEnon-polymer404.21Chemie (UDP)
4AGLYCEROLnon-polymer92.12Chemie (GOL)
5ASULFATE IONnon-polymer96.12Chemie (SO4)
6waterwater18.0317Chemie (HOH)
Sequence modifications
A: 64 - 354 (UniProt: P16442)
PDBExternal DatabaseDetails
Met 57-expression tag
Ala 58-expression tag
Ile 59-expression tag
Gly 60-expression tag
Glu 61-expression tag
Phe 62-expression tag
Met 63-expression tag
Gly 266Leu 266engineered mutation
Ala 268Gly 268engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34654.0
Non-Polymers*Number of molecules6
Total formula weight835.4
All*Total formula weight35489.4
*Water molecules are not included.

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PDB entries from 2024-04-24

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