5M5O
Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tubulin alpha-1D chain | polymer | 452 | 50236.4 | 1 | UniProt (Q2HJ86) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (Bovine) | |
2 | B | Tubulin beta-2B chain | polymer | 445 | 49907.8 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (Bovine) | |
3 | C | Kinesin-like protein cut7 | polymer | 369 | 40737.5 | 1 | UniProt (P24339) Pfam (PF00225) In PDB | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | Cell untimely torn protein 7 |
4 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
6 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
7 | B | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) | |||
8 | C | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) |
Sequence modifications
A: 1 - 452 (UniProt: Q2HJ86)
B: 1 - 445 (UniProt: Q6B856)
PDB | External Database | Details |
---|---|---|
Ile 7 | Val 7 | conflict |
Ile 114 | Leu 114 | conflict |
Ser 136 | Leu 136 | conflict |
Val 137 | Ile 137 | conflict |
Gly 265 | Ile 265 | conflict |
Glu 358 | Gln 358 | conflict |
Val 437 | Met 437 | conflict |
Glu 450 | Asp 450 | conflict |
PDB | External Database | Details |
---|---|---|
Ala 55 | Thr 55 | conflict |
Val 170 | Met 170 | conflict |
Ala 296 | Ser 296 | conflict |
Val 316 | Ile 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 140881.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2375.1 | |
All* | Total formula weight | 143256.7 |