5M3D

Structural tuning of CD81LEL (space group P31)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	CD81 antigen	polymer	101	11182.4	4	UniProt (P60033) Pfam (PF00335)	Homo sapiens (Human)	26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28
2	E, F, I, L, O... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
3	G, H, J, K, M... (B, C, D)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
4	Q, R (A, D)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B, C, D: 112 - 201 (UniProt: P60033)

PDB	External Database	Details
Glu 110	-	expression tag
Thr 111	-	expression tag
Gly 202	-	expression tag
Thr 203	-	expression tag
Lys 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	44729.7
Non-Polymers*	Number of molecules	12
	Total formula weight	942.2
All*	Total formula weight	45671.9

*Water molecules are not included.