5M37

The molecular tweezer CLR01 stabilizes a disordered protein-protein interface

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	14-3-3 protein zeta/delta	polymer	230	26316.8	2	UniProt (P63104) Pfam (PF00244)	Homo sapiens (Human)	Protein kinase C inhibitor protein 1,KCIP-1
2	C, D (C, D)	M-phase inducer phosphatase 3	polymer	20	2414.6	2	UniProt (P30307)	Homo sapiens	Dual specificity phosphatase Cdc25C
3	E, G, I, J (A, B, C, D)	(1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene	non-polymer		726.6	4	Chemie (9SZ)
4	F, H (A, B)	BENZOIC ACID	non-polymer		122.1	2	Chemie (BEZ)
5	K, L, M, N (A, B, C, D)	water	water		18.0	162	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	57462.8
Non-Polymers*	Number of molecules	6
	Total formula weight	3150.8
All*	Total formula weight	60613.6

*Water molecules are not included.