5M01
Crystal structure of murine P14 TCR/ H-2Db complex with PA, modified gp33 peptide from LCMV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | H-2 class I histocompatibility antigen, D-B alpha chain | polymer | 276 | 32087.7 | 1 | UniProt (P01899) Pfam (PF00129) Pfam (PF07654) | Mus musculus (House Mouse) | H-2D(B) |
| 2 | B (B) | Beta-2-microglobulin | polymer | 119 | 13795.0 | 1 | UniProt (P01887) Pfam (PF07654) | Mus musculus (House Mouse) | |
| 3 | C (G) | Protein Trav14-1,T-cell receptor alpha chain C region | polymer | 205 | 23072.7 | 1 | UniProt (A0A0G2JF94) UniProt (P01849) Pfam (PF07686) Pfam (PF09291) | Mus musculus (House Mouse) | |
| 4 | D (H) | T-cell receptor beta chain V region C5,T-cell receptor beta-2 chain C region | polymer | 238 | 26647.6 | 1 | UniProt (P04213) UniProt (P01851) Pfam (PF07686) Pfam (PF07654) | Mus musculus (House Mouse) | |
| 5 | E (P) | LCMV-DERIVED GP33 ALTERED PEPTIDE LIGAND PA | polymer | 9 | 951.1 | 1 | Lymphocytic choriomeningitis virus | ||
| 6 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | H, I, J, K, L (A, B, G, H, P) | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P01887)
G: 1 - 99 (UniProt: A0A0G2JF94)
G: 120 - 205 (UniProt: P01849)
H: 1 - 92 (UniProt: P04213)
H: 112 - 238 (UniProt: P01851)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Ala -18 | - | expression tag |
| Arg -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Val -15 | - | expression tag |
| Thr -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Val -12 | - | expression tag |
| Phe -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Val -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Val -7 | - | expression tag |
| Ser -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Met -1 | - | cloning artifact |
| Gly 0 | - | cloning artifact |
| Asp 85 | Ala 105 | variant |
| PDB | External Database | Details |
|---|---|---|
| Leu 100 | - | linker |
| Tyr 101 | - | linker |
| Gly 102 | - | linker |
| Asn 103 | - | linker |
| Glu 104 | - | linker |
| Lys 105 | - | linker |
| Ile 106 | - | linker |
| Thr 107 | - | linker |
| Phe 108 | - | linker |
| Gly 109 | - | linker |
| Ala 110 | - | linker |
| Gly 111 | - | linker |
| Thr 112 | - | linker |
| Lys 113 | - | linker |
| Leu 114 | - | linker |
| Thr 115 | - | linker |
| Ile 116 | - | linker |
| Lys 117 | - | linker |
| Pro 118 | - | linker |
| Asn 119 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Cys 166 | Thr 49 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asp 93 | - | linker |
| Ala 94 | - | linker |
| Gly 95 | - | linker |
| Gly 96 | - | linker |
| Arg 97 | - | linker |
| Asn 98 | - | linker |
| Thr 99 | - | linker |
| Leu 100 | - | linker |
| Tyr 101 | - | linker |
| Phe 102 | - | linker |
| Gly 103 | - | linker |
| Ala 104 | - | linker |
| Gly 105 | - | linker |
| Thr 106 | - | linker |
| Arg 107 | - | linker |
| Leu 108 | - | linker |
| Ser 109 | - | linker |
| Val 110 | - | linker |
| Leu 111 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Cys 168 | Ser 57 | conflict |
| Ser 182 | Cys 71 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96554.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 96738.3 |
