5LZY
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | uL2 | polymer | 257 | 28088.9 | 1 | UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 2 | B | uL3 | polymer | 403 | 46108.0 | 1 | UniProt (G1TL06) Pfam (PF00297) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 3 | C | uL4 | polymer | 425 | 47727.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 4 | D | 60S ribosomal protein L5 | polymer | 297 | 34481.8 | 1 | UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 5 | E | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 6 | F | uL30 | polymer | 247 | 29201.8 | 1 | UniProt (G1TUB1) Pfam (PF00327) Pfam (PF08079) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 7 | G | eL8 | polymer | 319 | 36221.5 | 1 | UniProt (G1STW0) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 8 | H | uL6 | polymer | 192 | 21871.4 | 1 | UniProt (G1TX33) Pfam (PF00347) UniProt (by SIFTS) (G1SWI6) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 9 | I | Ribosomal protein L10 (Predicted) | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) In PDB | Oryctolagus cuniculus (Rabbit) | Uncharacterized protein |
| 10 | J | uL5 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 11 | L | eL13 | polymer | 211 | 24331.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 12 | M | eL14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 13 | N | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 14 | O | uL13 | polymer | 203 | 23533.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 15 | P | uL22 | polymer | 184 | 21444.2 | 1 | UniProt (G1TVT6) Pfam (PF00237) UniProt (by SIFTS) (G1SCJ6) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 16 | Q | eL18 | polymer | 188 | 21699.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 17 | R | eL19 | polymer | 196 | 23535.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 18 | S | eL20 | polymer | 176 | 20827.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 19 | T | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 20 | U | eL22 | polymer | 128 | 14813.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 21 | V | eL14 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 22 | W | eL24 | polymer | 157 | 17825.1 | 1 | UniProt (G1SE28) Pfam (PF01246) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 23 | X | eL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 24 | Y | uL24 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 25 | Z | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 26 | a | uL15 | polymer | 148 | 16620.6 | 1 | UniProt (G1SNY0) Pfam (PF00828) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 27 | b | eL29 | polymer | 245 | 26708.7 | 1 | UniProt (G1SGR6) Pfam (PF01779) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 28 | c | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 29 | d | eL31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 30 | e | eL32 | polymer | 135 | 15898.9 | 1 | UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 31 | f | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 32 | g | eL34 | polymer | 117 | 13326.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 33 | h | uL29 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 34 | i | 60S ribosomal protein L36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 35 | j | eL37 | polymer | 97 | 11111.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 36 | k | eL38 | polymer | 70 | 8238.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 37 | l | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 38 | m | eL40 | polymer | 102 | 11699.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 39 | n | eL41 | polymer | 25 | 3473.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 40 | o | eL42 | polymer | 106 | 12477.0 | 1 | UniProt (G1U344) Pfam (PF00935) UniProt (by SIFTS) (G1T040) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 41 | p | eL43 | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 42 | r | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 43 | s | uL10 | polymer | 318 | 34380.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 44 | t | uL11 | polymer | 165 | 17847.6 | 1 | UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 45 | 2, 3 | tRNA | polymer | 75 | 24102.3 | 2 | Oryctolagus cuniculus (Rabbit) | ||
| 46 | 5 | 28S ribosomal RNA | polymer | 3543 | 1148115.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 47 | 7 | 5S ribosomal RNA | polymer | 120 | 38691.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 48 | 8 | 5.8S ribosomal RNA | polymer | 156 | 50143.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 49 | 9 | 18S ribosomal RNA | polymer | 1869 | 602778.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 50 | AA | uS2 | polymer | 295 | 32958.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 51 | BB | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 52 | CC | uS5 | polymer | 293 | 31327.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 53 | DD | uS3 | polymer | 243 | 26715.3 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 54 | EE | eS4 | polymer | 263 | 29654.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 55 | FF | uS7 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 56 | GG | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 57 | HH | eS7 | polymer | 194 | 22168.9 | 1 | UniProt (G1SVB0) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 58 | II | eS8 | polymer | 208 | 24263.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 59 | JJ | Ribosomal protein S9 (Predicted) | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 60 | KK | eS10 | polymer | 165 | 18933.8 | 1 | UniProt (G1TPV3) Pfam (PF03501) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 61 | LL | uS17 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 62 | MM | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 63 | NN | uS15 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 64 | OO | uS11 | polymer | 168 | 18134.0 | 1 | UniProt (G1T1F0) Pfam (PF00411) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 65 | PP | uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 66 | uS9 | polymer | 146 | 16477.4 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (Rabbit) | ||
| 67 | RR | eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 68 | SS | uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 69 | TT | eS19 | polymer | 145 | 16106.6 | 1 | UniProt (G1TN62) Pfam (PF01090) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 70 | UU | uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 71 | VV | eS21 | polymer | 83 | 9124.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 72 | WW | uS8 | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 73 | XX | uS12 | polymer | 143 | 15844.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 74 | YY | eS24 | polymer | 130 | 15107.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 75 | ZZ | eS25 | polymer | 125 | 13776.2 | 1 | UniProt (G1TDB3) Pfam (PF03297) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 76 | aa | eS26 | polymer | 115 | 13047.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 77 | bb | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 78 | cc | eS28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 79 | dd | uS14 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) Pfam (PF00253) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 80 | ee | eS30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 81 | ff | eS31 | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 82 | gg | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (Rabbit) | |
| 83 | hh | mRNA (polyadenylated) | polymer | 8 | 2588.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 84 | ii | Protein pelota homolog | polymer | 403 | 45519.3 | 1 | UniProt (Q9BRX2) Pfam (PF03463) Pfam (PF03464) Pfam (PF03465) In PDB | Homo sapiens (Human) | |
| 85 | jj | HBS1-like protein | polymer | 710 | 78638.0 | 1 | UniProt (Q9Y450) Pfam (PF08938) Pfam (PF00009) Pfam (PF03144) Pfam (PF03143) In PDB | Homo sapiens (Human) | ERFS |
| 86 | 5, 7, 9, 8, B... | MAGNESIUM ION | non-polymer | 24.3 | 236 | Chemie (MG) | |||
| 87 | aa, dd, g, ff, j... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 88 | jj | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (GCP) |
Sequence modifications
B: 2 - 403 (UniProt: G1TL06)
D: 2 - 297 (UniProt: G1SYJ6)
F: 1 - 247 (UniProt: G1TUB1)
G: 1 - 77 (PDB: 5LZY)
G: 78 - 319 (UniProt: G1STW0)
a: 1 - 148 (UniProt: G1SNY0)
b: 1 - 226 (UniProt: G1SGR6)
b: 227 - 245 (PDB: 5LZY)
OO: -16 - -5 (PDB: 5LZY)
OO: -4 - 151 (UniProt: G1T1F0)
TT: 1 - 145 (UniProt: G1TN62)
ii: 1 - 385 (UniProt: Q9BRX2)
jj: 1 - 684 (UniProt: Q9Y450)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Arg 61 | Gly 61 | conflict |
| Arg 93 | Gly 93 | conflict |
| Met 131 | Val 131 | conflict |
| Ile 153 | Val 153 | conflict |
G: 78 - 319 (UniProt: G1STW0)
| PDB | External Database | Details |
|---|---|---|
| Gly 244 | Cys 167 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | Gln 1 | conflict |
b: 227 - 245 (PDB: 5LZY)
OO: -16 - -5 (PDB: 5LZY)
OO: -4 - 151 (UniProt: G1T1F0)
TT: 1 - 145 (UniProt: G1TN62)
| PDB | External Database | Details |
|---|---|---|
| Gly 119 | Trp 119 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 221 | Leu 221 | variant |
| Gly 386 | - | expression tag |
| Ser 387 | - | expression tag |
| Glu 388 | - | expression tag |
| Asn 389 | - | expression tag |
| Leu 390 | - | expression tag |
| Tyr 391 | - | expression tag |
| Phe 392 | - | expression tag |
| Gln 393 | - | expression tag |
| Gly 394 | - | expression tag |
| Ala 395 | - | expression tag |
| His 396 | - | expression tag |
| His 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| Ser 402 | - | expression tag |
| Thr 403 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -25 | - | initiating methionine |
| Asp -24 | - | expression tag |
| Tyr -23 | - | expression tag |
| Lys -22 | - | expression tag |
| Asp -21 | - | expression tag |
| His -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Asp -14 | - | expression tag |
| His -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Tyr -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 86 |
| Total formula weight | 3536360.1 | |
| Non-Polymers* | Number of molecules | 245 |
| Total formula weight | 6780.5 | |
| All* | Total formula weight | 3543140.6 |
