5LZ5
Fragment-based inhibitors of Lipoprotein associated Phospholipase A2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Platelet-activating factor acetylhydrolase | polymer | 388 | 44203.1 | 1 | UniProt (Q13093) Pfam (PF03403) In PDB | Homo sapiens (Human) | PAF acetylhydrolase,1-alkyl-2-acetylglycerophosphocholine esterase,2-acetyl-1-alkylglycerophosphocholine esterase,Group-VIIA phospholipase A2,gVIIA-PLA2,LDL-associated phospholipase A2,LDL-PLA(2),PAF 2-acylhydrolase |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
3 | A | 2-fluoranyl-5-[2-[(4~{S})-4-methyl-2-oxidanylidene-4-phenyl-pyrrolidin-1-yl]ethoxy]benzenecarbonitrile | non-polymer | 338.4 | 1 | Chemie (7K4) | |||
4 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 46 - 428 (UniProt: Q13093)
PDB | External Database | Details |
---|---|---|
His 429 | - | expression tag |
His 430 | - | expression tag |
His 431 | - | expression tag |
His 432 | - | expression tag |
His 433 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44203.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 409.3 | |
All* | Total formula weight | 44612.4 |