5LYH
Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor H10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Poly [ADP-ribose] polymerase 14 | polymer | 193 | 22118.6 | 2 | UniProt (Q460N5) Pfam (PF00644) | Homo sapiens (Human) | PARP-14,ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2 |
| 2 | C, D (A, B) | 3-[2-[4-[2-[[4-[(3-aminocarbonylphenyl)amino]-4-oxidanylidene-butanoyl]amino]ethyl]-1,2,3-triazol-1-yl]ethylsulfamoyl]benzoic acid | non-polymer | 557.6 | 2 | Chemie (7B8) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A, B: 1611 - 1801 (UniProt: Q460N5)
| PDB | External Database | Details |
|---|---|---|
| Ser 1609 | - | expression tag |
| Met 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44237.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1115.2 | |
| All* | Total formula weight | 45352.3 |
