5LXX

High-resolution structure of human collapsin response mediator protein 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydropyrimidinase-related protein 2	polymer	501	55097.0	2	UniProt (Q16555) Pfam (PF01979)	Homo sapiens (Human)	DRP-2,Collapsin response mediator protein 2,CRMP-2,N2A3,Unc-33-like phosphoprotein 2,ULIP-2
2	C, D, E, F, H (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	G, I (A, B)	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	2	Chemie (BTB)
4	J, K (A, B)	water	water		18.0	1309	Chemie (HOH)

Sequence modifications

A, B: 13 - 490 (UniProt: Q16555)

PDB	External Database	Details
Met -10	-	initiating methionine
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Val 0	-	expression tag
Asp 1	-	expression tag
Leu 2	-	expression tag
Gly 3	-	expression tag
Thr 4	-	expression tag
Glu 5	-	expression tag
Asn 6	-	expression tag
Leu 7	-	expression tag
Tyr 8	-	expression tag
Phe 9	-	expression tag
Gln 10	-	expression tag
Ser 11	-	expression tag
Met 12	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	110193.9
Non-Polymers*	Number of molecules	7
	Total formula weight	898.8
All*	Total formula weight	111092.7

*Water molecules are not included.