5LXQ

Structure of PRL-1 in complex with the Bateman domain of CNNM2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, C)	Protein tyrosine phosphatase type IVA 1	polymer	196	22647.3	2	UniProt (Q63739) Pfam (PF22785)	Mus musculus (House Mouse)	Protein-tyrosine phosphatase 4a1,Protein-tyrosine phosphatase of regenerating liver 1,PRL-1
2	B, D (A, H)	Metal transporter CNNM2	polymer	156	17866.4	2	UniProt (Q3TWN3) Pfam (PF00571)	Mus musculus (House Mouse)	Ancient conserved domain-containing protein 2,mACDP2,Cyclin-M2
3	E, G (A, H)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
4	F, H (A, H)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

B, C: 1 - 173 (UniProt: Q63739)

PDB	External Database	Details
Met -22	-	initiating methionine
Ser -21	-	expression tag
Tyr -20	-	expression tag
Tyr -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Leu -12	-	expression tag
Glu -11	-	expression tag
Ser -10	-	expression tag
Thr -9	-	expression tag
Ser -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Lys -4	-	expression tag
Ala -3	-	expression tag
Gly -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag

A, H: 430 - 584 (UniProt: Q3TWN3)

PDB	External Database	Details
Met 429	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	81027.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1145.2
All*	Total formula weight	82172.5

*Water molecules are not included.