5LUC
Crystal structure of the D183N variant of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 1.8 Angstrom; internal aldimine with PLP in the active site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, E, G, M... | Serine--pyruvate aminotransferase | polymer | 403 | 44280.2 | 8 | UniProt (P21549) Pfam (PF00266) In PDB | Homo sapiens (Human) | SPT,Alanine--glyoxylate aminotransferase,AGT |
2 | A, B, E, G, M... | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 8 | Chemie (PLP) | |||
3 | A, B, E, G, M... | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 8 | Chemie (BTB) | |||
4 | water | water | 18.0 | 4154 | Chemie (HOH) |
Sequence modifications
A, B, E, G, M, N, S, T: 1 - 392 (UniProt: P21549)
PDB | External Database | Details |
---|---|---|
Met -10 | - | initiating methionine |
Gly -9 | - | expression tag |
Gly -8 | - | expression tag |
Ser -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
Gly 0 | - | expression tag |
Asn 183 | Asp 183 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 354241.2 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 3651.1 | |
All* | Total formula weight | 357892.3 |