5LUA
Crystal structure of human legumain (AEP) in complex with compound 11b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Legumain | polymer | 262 | 29944.6 | 2 | UniProt (Q99538) Pfam (PF01650) In PDB | Homo sapiens (Human) | Asparaginyl endopeptidase,Protease,cysteine 1 |
| 2 | C, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | B | 2,4-di(morpholin-4-yl)aniline | non-polymer | 263.3 | 1 | Chemie (5KN) | |||
| 5 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 287 (UniProt: Q99538)
| PDB | External Database | Details |
|---|---|---|
| Gln 263 | Asn 263 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59889.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 705.8 | |
| All* | Total formula weight | 61868.1 |
