5LU1
Human 14-3-3 sigma CLU3 mutant complexed with short HSPB6 phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (A, B, E, F) | 14-3-3 protein sigma | polymer | 234 | 26257.6 | 4 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | C, D, G, H (C, D, G, H) | Heat shock protein beta-6 | polymer | 8 | 949.0 | 4 | UniProt (O14558) | Homo sapiens | HspB6,Heat shock 20 kDa-like protein p20 |
| 3 | I, J, K, L (A, B, E, F) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 4 | Chemie (TRS) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
A, B, E, F: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 75 | Glu 75 | engineered mutation |
| Ala 76 | Glu 76 | engineered mutation |
| Ala 77 | Lys 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 108826.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 488.6 | |
| All* | Total formula weight | 109315.0 |
