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5LSO

Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
Splicing factor 45polymer10311534.32UniProt (Q96I25)
Pfam (PF00076)
Homo sapiens (Human)45 kDa-splicing factor,RNA-binding motif protein 17
2B, D
(C, D)
LYS-SER-ARG-TRP-ASP-GLUpolymer6821.92Homo sapiens
3E, F, G, H
(A, C, B, D)
waterwater18.0171Chemie (HOH)
Sequence modifications
A, B: 301 - 400 (UniProt: Q96I25)
PDBExternal DatabaseDetails
Ala 298-expression tag
Met 299-expression tag
Gly 300-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight24712.4
All*Total formula weight24712.4
*Water molecules are not included.

246333

PDB entries from 2025-12-17

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