5LSK
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein MIS12 homolog | polymer | 205 | 24170.9 | 1 | UniProt (Q9H081) Pfam (PF05859) | Homo sapiens (Human) | |
| 2 | B (B) | Polyamine-modulated factor 1 | polymer | 176 | 20522.4 | 1 | UniProt (Q6P1K2) Pfam (PF03980) | Homo sapiens (Human) | PMF-1 |
| 3 | C (D) | Kinetochore-associated protein DSN1 homolog | polymer | 296 | 33848.2 | 1 | UniProt (Q9H410) Pfam (PF08202) | Homo sapiens (Human) | |
| 4 | D (N) | Kinetochore-associated protein NSL1 homolog | polymer | 206 | 23307.6 | 1 | UniProt (Q96IY1) Pfam (PF08641) | Homo sapiens (Human) | |
| 5 | E (P) | Centromere protein C | polymer | 76 | 8501.5 | 1 | UniProt (Q03188) | Homo sapiens (Human) | CENP-C,Centromere autoantigen C,Centromere protein C 1,CENP-C 1,Interphase centromere complex protein 7 |
| 6 | F, G, H (A, B, P) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B: 31 - 205 (UniProt: Q6P1K2)
D: 68 - 356 (UniProt: Q9H410)
P: 1 - 71 (UniProt: Q03188)
| PDB | External Database | Details |
|---|---|---|
| Met 30 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 67 | - | initiating methionine |
| His 357 | - | expression tag |
| His 358 | - | expression tag |
| His 359 | - | expression tag |
| His 360 | - | expression tag |
| His 361 | - | expression tag |
| His 362 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 110350.6 | |
| All* | Total formula weight | 110350.6 |
