5LS1
CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR166475
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heat shock protein HSP 90-alpha | polymer | 207 | 23166.3 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
2 | A | 2-[(4-oxidanylidenecyclohexyl)amino]-4-(3,6,6-trimethyl-4-oxidanylidene-5,7-dihydroindol-1-yl)benzamide | non-polymer | 407.5 | 1 | Chemie (73Z) | |||
3 | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
A: 18 - 223 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
Met 17 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23166.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 407.5 | |
All* | Total formula weight | 23573.8 |