5LQS
Structure of quinolinate synthase Y21F mutant in complex with substrate-derived quinolinate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Quinolinate synthase A | polymer | 305 | 34640.6 | 1 | UniProt (Q9X1X7) Pfam (PF02445) | Thermotoga maritima MSB8 | |
| 2 | B (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 3 | C (A) | QUINOLINIC ACID | non-polymer | 167.1 | 1 | Chemie (NTM) | |||
| 4 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F (A) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: Q9X1X7)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Phe 21 | Tyr 21 | engineered mutation |
| Arg 219 | Lys 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34640.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 589.7 | |
| All* | Total formula weight | 35230.3 |
