5LNP
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, C, D) | Segment polarity protein dishevelled homolog DVL-2 | polymer | 97 | 10862.4 | 3 | UniProt (O14641) Pfam (PF00610) | Homo sapiens (Human) | Dishevelled-2,DSH homolog 2 |
| 2 | B (B) | Segment polarity protein dishevelled homolog DVL-2 | polymer | 97 | 10846.4 | 1 | UniProt (O14641) Pfam (PF00610) | Homo sapiens (Human) | Dishevelled-2,DSH homolog 2 |
| 3 | E (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A, C, D: 416 - 510 (UniProt: O14641)
B: 416 - 510 (UniProt: O14641)
| PDB | External Database | Details |
|---|---|---|
| Ser 414 | - | expression tag |
| Ser 415 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 414 | - | expression tag |
| Ser 415 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43433.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 43529.5 |
